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ERITROCITOSIS PATOLÓGICA DE ALTURA: Caracterización biológica, diagnóstico y tratamiento. HIGH ALTITUDE PATHOLOGICAL ERYTHROCYTOSIS. Diagnóstico y tratamiento | 23 DIC Eritrocitosis. Actualización de los métodos diagnósticos y el manejo de los pacientes con eritrocitosis. 3. original research. DOI: Secondary erythrocytosis due to hypoxemia as prognosis. in exacerbated chronic .
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Guided by the value of prognostic factors evaluated during exacerbations, it is assumed that the presence of erythrocytosis may increase or decrease the risk twice for the combined outcome. Universidad Nacional de Colombia.
Cardiovascular events and intensity of treatment in polycythemia vera. Patients with congenital heart disease, for whom diagnosis of exacerbation of lung disease was discarded at discharge, and those who did not wish to participate in the study were excluded from the study. Hemoglobin levels above anemia thresholds are maximally predictive for long-term survival in COPD with chronic respiratory failure.
The results suggest the need for further studies to clarify the relevance of erythrocyte parameters in exacerbations of chronic lung disease, both at sea level and in populations located at higher altitudes, as in this case. At admission, five patients had a history of phlebotomy and hematocrits were located preferentially in the last interquartile or near this range.
While the minority of patients eritrociosis a severe functional class IVthe use of long-acting bronchodilators was limited to only five cases, compared with the more extensive use of methylxanthines. Mortality and mortality-related factors after hospitalization for acute exacerbation of COPD. N Engl J Med ; The presence of comorbidity was high, especially in women; among them, hypertension was the most prevalent comorbidity, followed by heart failure and diabetes mellitus type 2.
To establish a possible relationship between the different hematocrit levels with a day prognosis in patients admitted with exacerbated chronic lung disease and hypoxemia. Discussion This study attempted to establish the relationship between red blood cell parameters and the development of adverse outcomes at 30 days in patients with exacerbated chronic lung disease.
The effects of therapeutic decrease in packed cell volume on the responses to exercise of patients with polycythaemia secondary to lung disease. Eriyrocitosis J Haematol ; Vascular and neoplastic risk in a large cohort of patients with polycythemia vera. For bivariate analysis, the Mann-Whitney U test was performed.
Clinical and paraclinical characteristics of patients included in the study by sex and hematocrit levels in percentiles.
The multivariate analysis did not include erythrocyte parameters given the lack of statistical significance of the data provided by these variables with the outcome. History of cerebrovascular disease. Conflict of interests None stated by the authors. Chronic obstructive pulmonary disease. This study attempted to establish the relationship between red blood cell parameters and the development of adverse outcomes at 30 days in patients with exacerbated chronic lung disease.
The variables that were statistically significant showed some unusual associations, particularly with the Anthonisen classification and the presence of a history of heart failure, the latter being a protective factor, without defining a coherent explanation for this finding and without any publication report with a similar result that could be used to infer that protective effect.
A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia vera. The outcome variable was a composite between death, length of hospital stay in floors, need for invasive or non-invasive ventilatory support, need to transfer to ICU and rehospitalization, provided that they were associated with chronic lung disease.
Haemoglobin level and its clinical impact in a cohort of patients with COPD. Regarding the outcomes, there was a predilection to higher length hospital stay in the presence of lower levels of hematocrit. Phlebotomy was performed in only three patients; indications focused on the hematocrit value and the technique used was variable in each case without having a direct relationship between the volume of blood extracted and the change of red cell values, in fact, in one patient no changes were seen.
Predictors of outcomes in COPD exacerbation cases presenting to the emergency department. Outcome measures The outcome variable was a composite between death, length of hospital stay in floors, need for invasive or non-invasive ventilatory support, need to transfer to ICU and rehospitalization, provided that they were associated with chronic lung disease.
Even though exacerbations are the main cause of emergency consultation in patients suffering from lung diseases, erythrocyte parameters are not assessed in their prognosis. Effects of theophylline on erythropoietin production in normal subjects and in patients with erythrocytosis after renal transplantation. Secondary erythrocytosis due to hypoxemia as prognosis in exacerbated chronic pulmonary diseases.
Pulmonary vascular disease in adults with congenital heart disease. Adults with cyanotic congenital heart disease: Asthma cases had an exclusive distribution in women.
This tartamiento could not determine any relationship between erythrocyte parameters and prognosis of patients suffering from pulmonary diseases; nevertheless, extreme values of hematocrits tended to have adverse outcomes. The following operating variables were established as admission and eritrocifosis analysis criteria: Almost half of patients had a history of smoking and it was two times higher in men compared to women.
Efficacy and safety of low-dose aspirin in polycythemia vera. In long-term observations, anemia has been identified as a factor involved in the development of adverse events in patients with stable chronic lung disease, whereas erythrocytosis has shown its inference on a better prognosis Cochrane Tratamlento Syst Rev ;4: Long term domiciliary oxygen therapy in chronic hypoxic cor pulmonale complicating chronic bronchitis and emphysema: Therefore, there is a big gap in the state of the art, which indicates the need to expand clinical research to achieve a better characterization of the risk tratmaiento the need for treatment of secondary erythrocytosis in stable and exacerbated chronic lung disease.
The definition of chronic lung disease that was coined sought to be sensible, considering that few patients have pulmonary physiology studies and that some of those who actually had them were not available at the time of the survey or follow-up.
Regarding red tratamidnto cell parameters, a tendency to have a protective effect when located in the core values of hematocrit against extreme values, this difference did not show a statistical significance. Int Med J ; Therapeutic recommendations in polycythemia vera based on Polycythemia Vera Study Group protocols. In only one case phlebotomy was repeated.
The prognostic value of this variable in the exacerbation has not been evaluated to date. No relationship between a history of use of home oxygen and hematocrit values was found.